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Infection with HPV is common, and in most cases the body can clear the infection on its own. For instance, in African Americans younger than age 60, it's more common in men than in women, but after age 60 it's more common in women. Other subtypes of HPV can cause warts in the genital and anal areas, but not cancer. In men, it would seem likely that having had penile cancer , which is also linked to HPV infection, would increase the risk of anal cancer, but this link has not been shown in studies. Women who have had cancer of the cervix , vagina , or vulva are at increased risk of anal cancer. Current smokers are several times more likely to have cancer of the anus compared with people who do not smoke.

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