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For hybrid chickens with sexually differentiated hatchling color, see Sex-link. If the father is affected, the son will always be unaffected, but the daughter will always be affected. Dyskeratosis congenita Hypohidrotic ectodermal dysplasia EDA X-linked ichthyosis X-linked endothelial corneal dystrophy. In the ZW sex-determination system used by birds, the mammalian pattern is reversed, since the male is the homogametic sex ZZ and the female is heterogametic ZW. These are characters only expressed in one sex. All males possessing an X-linked recessive mutation will be affected, since males have only a single X chromosome and therefore have only one copy of X-linked genes. Annual Review of Ecology and Systematics.

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